Within the confines of the course management system, yes my sites are accessible. I do it because I require my students design their applications to be accessible. I am a lot of things, but generally not a hypocrite. I believe in accessibility quite strongly. My principle is this : do as much as you can with the tools you have and try and learn one more technique for next semester.
When writing (X)HTML: make sure your code is validated under the W3C validation rules. That will get you very close. You may also wish to download or use an online accessibility checker (e.g. Firefox Accessibility toolbar, WAVE, Cynthia Says, etc)
Physical - I make sure all my on-page actions are accessible via a mouse and keyboard. Not hard, but can be a little tricky depending.
Hearing: All my videos are captioned either with closed or open captioning. I use Camtasia (the Windows version has a pretty good speech to text module that makes this a little easier) but there are others. Alan started a good
thread some time back that talked more about this.
This biggest drawback will always be the CMS. Most claim to be accessible to some degree. Good luck - some of your students will appreciate your effort.
Happy to help over PM if there is a specific thing you want to work on.