Patient Dies in Gene-Therapy Trial at University of Pennsylvania Medical Center

An 18-year-old patient died late last month at the University of Pennsylvania Medical Center, shortly after receiving an infusion of genetically altered viruses in a gene-therapy experiment. The event has halted that study and caused federal officials to ask all researchers using similar viruses to scrutinize their records for evidence of any side effects.

"This was obviously a shock and a source of great sadness," said Steven Raper, an associate professor of

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